Before you make any changes in your Windows Registry where you're not completely sure of what you are doing, it might be a good idea to make a backup of your current registry settings. You can either do that by
Back up Files on Windows with HoboCopy
HoboCopy is a commandline program that lets you copy large amounts of data in a comparatively short time to other copy functions. However, the clue is that it takes a snapshot of the file system before copying, making it possible
Reduce load of backup scripts with nice and ionice
Runing a nightly backup script on a server system like a webhosting server can produce high load and longer latencys for other processes, e.g. HTML or .php pages load slow during backup because the backup script takes too much I/O